Regularly evaluate men on treatment for prostate cancer risk including PSA testing. Establish new PSA baseline after 6 mth of treatment. Monitor PSA values regularly thereafter. Perform digital rectal exam & other prostate cancer evaluations on BPH patients prior to initiating therapy & periodically thereafter. Orthostatic/symptomatic hypotension; intraoperative floppy iris syndrome. Discontinue therapy 1-2 wk prior to cataract surgery. Concomitant use w/ strong CYP3A4 (eg, ketoconazole) or CYP2D6 (eg, paroxetine) inhibitors; PDE5 inhibitors. Patients taking moderate CYP3A4 inhibitor (eg, erythromycin), strong or moderate CYP2D6 inhibitor, combination of both CYP3A4 & CYP2D6 inhibitors, or in patients known to be poor metabolizers of CYP2D6. Patients w/ liver disease. May affect ability to drive & use machines as symptoms related to orthostatic hypotension eg, dizziness can possibly occur. Mild to moderate hepatic impairment. Avoid contact w/ leaking cap in women, childn & adolescents.
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